Question 22 STRs are useful for DNA profiling because they O are easily connected to human phenotype O are highly variable in human populations O code for proteins O are strongly influenced by selection Question 23 What is predictive DNA Phenotyping?
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- Fig 3.16 EcoRI SacI KpnI |ampR Aval Xmal Smal lacZ BamHI Xbal SalI Accl HincII PstI Sphl HindIII Bam H1 Bam H1 Bam H1 1 2 3 4 The ends of the double-stranded DNA fragment above are blunt ends. The directionality of genes contained within the fragment is from left to right (arrow). After digestion by BamH1, which fragment can be inserted into the vector cut with BamH1 and Sma 1 maintaining the same directionality as the lacz promoter (green segment with arrow on vector)? 3 O 4 O1 2Variations in Phenotype Expression A genetic disorder characterized by falling asleep in genetics lectures is known to be 20% penetrant. All 90 students in a genetics class are homozygous for this gene. Theoretically, how many of the 90 students will fall asleep during the next lecture?Question 17 How do we go from a genetic association to a causal relation between a gene and a phenotype? ◇ We can use a GWAS with many different samples to identify causal alleles. O We can quantify gene expression of a gene of interest and determine the relationship with a phenotype. O We can determine how often an associated allele occurs in cases that have a disease, which will allow us to determine a causal relationship. By silencing a gene, we can study the effect of that gene on the phenotype. Question 18 What is the function of the CRISPR-Cas system in nature? O part of the bacterial immune response against viral infection a molecule involved in regulation of expression
- 66 Comparisons of DNA sequences among humans have revealed many types of variations. Which of the following variations involves duplication of relatively long stretches of DNA? Select one alternative: O Copy number variants O Single nucleotide polymorphisms O Short tandem repeats O DNA ligationQUESTION 8 Which statement about SNPS in the human genome is true? O Most SNPS are located in the introns of genes, and thus effect phenotype. Any two human genome copies will have on average 3 million single nucleotide polymorphisms. Most SNPS have an effect on phenotype. SNPS refer only to deletions or insertions, not base substitutions.Question Which example is describing a "nonsense" mutation? O The normal amino acid sequence of a protein is Met-Ala-Phe-Tyr and the mutated allele produces an amino acid sequence Met-Ala-Phe-Leu O The normal amino acid sequence of a protein is Met-Ala-Phe Tyr and the mutated allele produces an amino acid sequence Met-Ala-Phe-Tyr O The normal amino acid sequence of a protein is Met-Ala-Phe-Tyr and the mutated allele produces an amino acid sequence Met-Ala-STOP Moire to the net question prevents changes to this angN
- Question 7 What is the function of primase? It O synthesizes an RNA primer. O separates DNA strands. synthesizes the DNA O joints Okazaki fragments. O removes primer.Help me please7:12 What is not true for Sequence tagged site (STS) markers: O cannot be mapped by fluorescence in situ hybridization (FISH) O subset of STS markers are known as expressed sequence tag (EST) markers O can readily be screened by a PCR assay O short DNA sequences that occur at a unique location in the genome
- Question 11 What statement is FALSE regarding the use linkage mapping for human genetics? O The first linkage map showed the relative location of genetic markers. OA large number of chromosomes means that many traits assort independently, frustrating linkage mapping efforts. O Linkage mapping continues to be the preferred method to determine alleles associated with disease. Initial linkage mapping used family pedigrees. Question 12 Which of the following is not a component of Sanger sequencing?G where can Question 29 Not yet answered Points out of1.00 P Flag question When a gene is re-ordered on a chromosome, this is called example of this is the evolution of humans from chimpanzees. About 4,04 An https://www ribosom Palade, who Select one: eukaryotic c O a. Inversion People O b. Insertion Where can O c. Duplication Where are O d. Deletion Can riboso Where can Time left 0:55:56 Next pa DELL| Choose ) [ Choose] metagenomics whole-genome shotgun approach bioinformatics ed GenBank genomics
