Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 45.1, Problem 1CC
How do response mechanisms in target cells differ for water-soluble and lipid-soluble hormones?
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How do response mechanisms in target cells differfor water-soluble and lipid-soluble hormones?
What are the diff erences among permissive eff ects, synergistic eff ects, and antagonistic eff ects of hormones?
One such laboratory study investigated the binding of a hormone to three different receptor proteins in the cell membrane. The data collected are shown in the table below
1) Provide a brief explanation as to why ligand binding toproteins must be a reversible process.
2) Calculate the dissociation constant (Kd) for the hormone binding to each of the three proteins.
Chapter 45 Solutions
Campbell Biology
Ch. 45.1 - How do response mechanisms in target cells differ...Ch. 45.1 - What type of gland would you expect to secrete...Ch. 45.1 - WHAT IF? Predict what would happen if you...Ch. 45.2 - What are the roles of oxytocin and prolactin in...Ch. 45.2 - How do the two fused glands of the pituitary gland...Ch. 45.2 - WHAT IF? 2192 Propose an explanation for why...Ch. 45.2 - what if? Lab tests of two patients, each...Ch. 45.3 - If a hormone pathway produces a transient response...Ch. 45.3 - Prob. 2CCCh. 45.3 - Prob. 3CC
Ch. 45 - MAKE CONNECTIONS What forms of signaling activate...Ch. 45 - Which major endocrine organs described in Figure...Ch. 45 - Prob. 45.3CRCh. 45 - Prob. 1TYUCh. 45 - Prob. 2TYUCh. 45 - Growth factors are local regulators that (A) are...Ch. 45 - Prob. 4TYUCh. 45 - Prob. 5TYUCh. 45 - Which of the following is the most likely...Ch. 45 - The relationship between the insect hormones...Ch. 45 - DRAW IT In mammals, milk production by mammary...Ch. 45 - Prob. 9TYUCh. 45 - Prob. 10TYUCh. 45 - Level 3: Synthesis/Evaluation 11. WRITE ABOUT A...Ch. 45 - Prob. 12TYU
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- Under in vivo conditions, chronic treatment with a noncompetitive antagonist may lead to the up-regulation of the targeted receptor over time. True False Cytokines are peptides that are generally made in advance by specific types of cells, stored in vesicles, and act as autocrine or paracrine factors. True False Thyroid hormone is stored in an extracellular compartment. True Falsearrow_forwardWhat characteristics of a hormone receptor make itspecific for one type of hormone?arrow_forwardWhich of the following is not a true statement? A.) steroid and thyroid hormone signaling would be impaired if the plasma level of carrier proteins is not optimal. B.) Steroid and thyroid hormone-receptor complexes form dimers when they bind to the hormone-response elements on DNA C.) Epinephrine uses the adenylate cyclase and the phospholipase C second messenger systems D.) signaling by a peptide hormone would be impaired if a second messenger system is not functional in the target cell E.) signaling by a steroid hormone would be hindered if the adenylated cyclase second messenger system is not functional in the target cell.arrow_forward
- How does the receptor location differ for lipid- versus water-soluble hormones and why?arrow_forwardWhat are the broad characteristics that distinguish a chemical substance from a hormone, and how can hormones attain specificity for certain types of target cells?arrow_forward24. To be considered a target cell for a particular hormone, a cell must …. a) be experiencing a disruption in homeostasis. b) be the same cell type as the one that produced the hormone. c) be capable of producing that hormone. d) be located relatively close to the cells that produced the hormone. e) have receptors that recognize and bind to the hormone.arrow_forward
- ● What is the mechanism of action of epinephrine, including its signaling mechanism(s), second messengers, target organs, and metabolic impacts?arrow_forwardDistinguish between the steroid and nonsteroid group of nuclear hormone receptors. Explain the central role of vitamin A in the actions of the nonsteroid group of receptors.arrow_forwardWhy are eicosanoids often referred to as "local hormones"?arrow_forward
- Explain how vinclozolin acts as an endocrine disrupter.arrow_forwardAll of the following statements relating to endocrine signaling are correct EXCEPT:arrow_forwardPlease identify the incorrect statement about hormone signaling: A) Cystolic receptors bind to hydophobic hormones and transport them into the nucleus where they directly influence protein synthesis. B) Hydropholic hormones cannot pass through the plasma membrane without help. Therefore, there are transport proteins that carry the hydrophillic hormones to the cytosol where it can bind its receptor C) Hydrophilic hormone signalling involves membrane receptors that have the ability to activate adenylyl cyclase, producing cAMP. cAMP then affects the activity of numerous proteins in the cytoplam. D) Hydrophobic hormones easily enter the plasma membrane. Therefore, there is no need for hydrophinic hormone receptors to be on the extracellular surface.arrow_forward
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