Tay-Sachs is a recessive lethal disease in which thereis neurological deterioration early in life. This diseaseis rare in the population overall but is found at relatively high frequency in Ashkenazi Jews from EasternEurope. A woman whose maternal uncle had the disease is trying to determine the probability that sheand her husband could have an affected child. Her father does not come from a high-risk population. Herhusband’s sister died of the disease at an early age.a. Draw the pedigree of the individuals described.Include the genotypes where possible.b. Determine the probability that the couple’s firstchild will be affected.

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Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.