Explain how bacteria can become resistant to ampicillin. Be sure to mention the following terms: peptidoglycan, beta lactamase, transpeptidase, beta lactam.
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- Explain how bacteria can become resistant to ampicillin. Be sure to mention the following terms: peptidoglycan, beta lactamase, transpeptidase, beta lactam.
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- A pathogenic bacteria ferments for survival in your patient producing a swollen, dark discolored leg due to muscles degradation and gas-filled distension on the skin. Treatment includes pressurized hyperbaric oxygen. Which of the following apply? None of the statements apply Streptococcus pneumoniae causing community aquired pneumonia. Klebsiella pneumoniae causing cellular degradation in pulmonary tissues Clostridium perfringens causing gas gangrene resulting in myonecrosis by synthesis of acids and gases Staphylococcus aureus producing lipases and proteasesDiscuss the virulence of bacterial pathogens on the basis of proteinase activity.Give two reasons why E. coli is naturally resistant to antibiotics like Penicillin?
- The ribosome is the target for many important antibiotics. These drugs must discriminate between bacterial and eukaryotic ribosomes to achieve drug specificity and toxicity. For the two common antibiotics below, what is their mechanism of action and why are they more toxic to bacteria than eukaryotes? a) Tetracycline b) ErythromycinBelow, you can see a picture of an antimicrobial drug. Regarding semi-synthetic antimicrobial drug development to try to avoid development of antibiotic resistance, use 1 sentence to address what is the significance/value of the presence of the various R-groups (e.g. R4, R5, R6, etc.)?Changes in the bacterial genome can lead to resistance to antimicrobialdrugs. what the different ways that these changes in the DNA occur?
- Give all the different antimicrobial metabolites in bacteria.What is the mode of action for kanamycin? Is it bacteriostatic or bactericidal? https://pubchem.ncbi.nlm.nih.gov/compound/KanamycinAminoglycosides and ß-lactams are commonly used antibiotics. Write a short account for both antibiotics respectively regarding their antibiotic classes, ways of inhibiting microorganisms and their specificities.
- What is the main group of microorganisms producing the most antibiotics? Describe the biochemical characteristics of this microorganism and provide TWO (2) examples of antibiotics produced by these microbes.What are two possible reasons for choosing a bacteriostatic treatment over a bactericidal one? Name the factors that can compromise the effectiveness of a disinfecting agentDefine the term cytopathic effect and provide one example.