5. Examine the graphic below and answer the questions about the enzyme we reviewed in lecture. 1.0 0.01 mM Vo АТР Vmax 1 mM ATP 0.5 1 mM ATP + 0.1 mM AMP 1 [Fru-6-P] (mM) 2 A) What enzyme is this? What reaction does it perform? Of what metabolic pathway is this enzyme a part? B) What allosteric regulator, shown on the graph as presented here, is considered to be a homotropic allosteric factor? C) Which allosteric regulator, shown on the graph as presented here, has the greatest influence on this enzyme? Explain the reasoning behind your answer. D) Name a positive allosteric effector of this enzyme NOT shown on the graph as presented here. What is the origin of this positive allosteric effector..that is, where is it coming from? E) Name a negative allosteric effector of this enzyme NOT shown on the graph as presented here. What is the origin of this negative allosteric effector,..that is, where is it coming from? F) Explain how the regulation of this enzyme is tied to the "energy state" of the cell.
Electron Transport Chain
The electron transport chain, also known as the electron transport system, is a group of proteins that transfer electrons through a membrane within mitochondria to create a gradient of protons that drives adenosine triphosphate (ATP)synthesis. The cell uses ATP as an energy source for metabolic processes and cellular functions. ETC involves series of reactions that convert redox energy from NADH (nicotinamide adenine dinucleotide (NAD) + hydrogen (H)) and FADH2(flavin adenine dinucleotide (FAD)) oxidation into proton-motive force(PMF), which is then used to synthesize ATP through conformational changes in the ATP synthase complex, a process known as oxidative phosphorylation.
Metabolism
Picture a campfire. It keeps the body warm on a cold night and provides light. To ensure that the fire keeps burning, fuel needs to be added(pieces of wood in this case). When a small piece is added, the fire burns bright for a bit and then dies down unless more wood is added. But, if too many pieces are placed at a time, the fire escalates and burns for a longer time, without actually burning away all the pieces that have been added. Many of them, especially the larger chunks or damp pieces, remain unburnt.
Cellular Respiration
Cellular respiration is the cellular process involved in the generation of adenosine triphosphate (ATP) molecules from the organic nutritional source obtained from the diet. It is a universal process observed in all types of life forms. The glucose (chemical formula C6H12O6) molecules are the preferred raw material for cell respiration as it possesses a simple structure and is highly efficient in nature.
![5. Examine the graphic below and answer the questions about the enzyme we reviewed in lecture.
1.0
0.01 mM
Vo
Vmax
ATP
1 mM ATP
0.5
1 mM ATP
+ 0.1 mM AMP
1
[Fru-6-P]
(mM)
2
A) What enzyme is this? What reaction does it perform? Of what metabolic pathway is this enzyme a part?
B) What allosteric regulator, shown on the graph as presented here, is considered to be a homotropic allosteric
factor?
C) Which allosteric regulator, shown on the graph as presented here, has the greatest influence on this enzyme?
Explain the reasoning behind your answer.
D) Name a positive allosteric effector of this enzyme NOT shown on the graph as presented here. What is the
origin of this positive allosteric effector...that is, where is it coming from?
E) Name a negative allosteric effector of this enzyme NOT shown on the graph as presented here. What is the
origin of this negative allosteric effector...that is, where is it coming from?
F) Explain how the regulation of this enzyme is tied to the "energy state" of the cell.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Febf69e27-3b27-4f98-a09a-8579a8586d1c%2F5e7bacd2-2c4c-4e56-8608-99a2fa2f77a7%2Fjaqsnrq_processed.png&w=3840&q=75)
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